tag:blogger.com,1999:blog-5491220859163652191.post8007867105899789670..comments2024-02-25T13:20:09.766-08:00Comments on Stranger than you can imagine: Discussion of financial interestdaedalus2uhttp://www.blogger.com/profile/10416564922288784455noreply@blogger.comBlogger6125tag:blogger.com,1999:blog-5491220859163652191.post-47771619542604513792007-06-19T11:06:00.000-07:002007-06-19T11:06:00.000-07:00As I mention, the notion of a "cure" means differe...As I mention, the notion of a "cure" means different things to different people. There is no treatment that will change the neural structures that are laid down in utero. That part of ASDs isn't going to change. <BR/><BR/>The greatest dysfunction associated with ASDs (according to ASDs) is not due to the neural structures, it is due to the "melt-downs" that occur. Raising the threshold for a "melt-down" to occur is (I think) the major effect that most ASDs would observe on my stuff. <BR/><BR/>The biggest dysfunction of ASDs according to "curbie" parents is that their children are "unlovable". That is not a problem with the child, that is a problem with the adult.daedalus2uhttps://www.blogger.com/profile/10416564922288784455noreply@blogger.comtag:blogger.com,1999:blog-5491220859163652191.post-76990378188642122272007-06-19T10:48:00.000-07:002007-06-19T10:48:00.000-07:00Thanks. I just feel the need to apologize when I ...Thanks. I just feel the need to apologize when I feel apologies are due. I have now seen many of your comments on other blogs, and realize how much I mistook your posts on Kev's blog. <BR/>I am opposed to harmful (or potentially harmful) treatments that are sold under the guise of "curing" autism. <BR/>On the other hand, I am all for safe treatments that can truly make lives of ASD folks easier or more enjoyable in any way.Jhttps://www.blogger.com/profile/10831843534657098189noreply@blogger.comtag:blogger.com,1999:blog-5491220859163652191.post-75444270429822684712007-06-19T04:28:00.000-07:002007-06-19T04:28:00.000-07:00Steve, That is ok, I wasn't offended. Your quest...Steve, That is ok, I wasn't offended. Your question is an understandable one, considering the fraud and dishonesty that the quacks have put out there. <BR/><BR/>I appreciate that I am making what some would consider extraordinary claims. I don't feel that the claims are extraordinary. I think they quite logically follow from what is well known about NO, and the observations I have made on how NO has affected my Asperger's. I recognize that my subjective observations are not compelling evidence for anyone but myself (and people who knew me before, and so can see the obvious and otherwise inexplicable change that there has been).daedalus2uhttps://www.blogger.com/profile/10416564922288784455noreply@blogger.comtag:blogger.com,1999:blog-5491220859163652191.post-29143468975604665072007-06-18T21:13:00.000-07:002007-06-18T21:13:00.000-07:00Daedalus - I am commenting here because it was I w...Daedalus - <BR/>I am commenting here because it was I who made the comments that prompted you to do this post. I was directly questioning your intentions, and I apologize for that. While I am sure you understand the basis of my skepticism, it does not excuse the way in which I made the comments. I commend you for your research, and look forward to the results.Jhttps://www.blogger.com/profile/10831843534657098189noreply@blogger.comtag:blogger.com,1999:blog-5491220859163652191.post-69542309267663700652007-05-02T12:45:00.000-07:002007-05-02T12:45:00.000-07:00There are several mechanisms. In humans, there ar...There are several mechanisms. In humans, there are veins from the scalp that drain through the skull, called emissary veins. into the venous sinuses in the brain. While NO as NO probably couldn't make it, a number of NO species could, including nitrite, S-nitrosoalbumin, S-nitrosohemoglobin, nitrosyl heme, and perhaps others.<BR/><BR/>NO via airway is not a good way of delivering systemic NO because the oxygenated hemoglobin destroys it at essentially diffusion limited kinetics. The venous blood in the scalp has lower O2 tension, so NO is going to have a longer half life (but probably still too short to make it as NO). <BR/><BR/>When the venous blood leaves the major sinuses in the brain, it passes through retes where it passes counter current with arterial blood. There is some data that in pigs, some steroid hormones are transported from the venous blood to the arterial blood. If hormones could make it, perhaps NO or other NO species could make it too.daedalus2uhttps://www.blogger.com/profile/10416564922288784455noreply@blogger.comtag:blogger.com,1999:blog-5491220859163652191.post-31968905860897202612007-05-02T12:28:00.000-07:002007-05-02T12:28:00.000-07:00How do you propose that topical nitric oxide on th...How do you propose that topical nitric oxide on the scalp can reach the brain?<BR/><BR/>Not to say that's impossible, since I have seen 1 paper describing a dose-dependent increase in the pig's brain when given NO via the airway.<BR/><BR/>You seem to be very well-versed, so I'd like to hear your description.<BR/><BR/>Thanks.Oscarhttps://www.blogger.com/profile/17026995802049657533noreply@blogger.com